Product Information:

XALTIDE HFA 100 MDI is a pressurized metered-dose inhaler (pMDI) containing Fluticasone Propionate 100mcg per actuation, an inhaled corticosteroid (ICS). It is delivered via hydrofluoroalkane (HFA) propellant, which is environmentally friendly and free of chlorofluorocarbons (CFCs).

This medication reduces airway inflammation and is used for the long-term maintenance treatment of asthma in adults and children. It is not intended for acute bronchospasm or status asthmaticus.

Uses of (XALTIDE HFA 100 MDI):

1. Maintenance treatment of persistent asthma
2. Prevention of asthma symptoms (wheezing, shortness of breath, chest tightness)
3. Reduction of asthma exacerbations and need for rescue inhalers
4. Long-term control in patients requiring low-to-medium dose inhaled corticosteroid therapy

Key Benefits of (XALTIDE HFA 100 MDI):

1. Potent anti-inflammatory action directly in the airways
2. Reduces airway hyperresponsiveness and mucus production
3. Once- or twice-daily dosing improves adherence
4. HFA propellant is ozone-safe and provides consistent delivery

How To Use (XALTIDE HFA 100 MDI):

1. Shake well before each use.
2. Remove cap and breathe out fully.
3. Place mouthpiece in mouth, seal lips tightly.
4. Press canister while inhaling slowly and deeply through the mouth.
5. Hold breath for 10 seconds, then exhale gently.
6. If more than one puff is prescribed, wait 30–60 seconds between puffs.
7. Rinse mouth with water after each use to prevent oral thrush and hoarseness.
8. Typical dosage:
9. Adults & adolescents ≥12 years: 1–2 puffs twice daily
10. Children 4–11 years: 1 puff twice daily (as directed by physician)
11. Not for acute attacks—always carry a rescue inhaler (e.g., salbutamol)

When Not to Use (XALTIDE HFA 100 MDI):

Do not use if you have:

1. Hypersensitivity to fluticasone propionate or any excipients
2. Acute asthma attack, status asthmaticus, or rapidly deteriorating asthma
3. Untreated fungal, bacterial, or viral respiratory infections (e.g., tuberculosis, herpes simplex)

Side Effects of (XALTIDE HFA 100 MDI):

Common:

1. Oral candidiasis (thrush)—reduced by rinsing mouth
2. Hoarseness, throat irritation
3. Cough, dry mouth

Less common:

1. Bruising, adrenal suppression (with long-term high-dose use)
2. Growth retardation in children (monitor height regularly)

Serious (rare):

1. Paradoxical bronchospasm—discontinue if breathing worsens
2. Glaucoma or cataracts (with prolonged ICS use)
3. Adrenal insufficiency (if stopped abruptly after long-term high-dose therapy)
4. Seek medical help if vision changes, worsening respiratory symptoms, or signs of systemic steroid effects occur.

Dosage: (XALTIDE HFA 100 MDI):

1. Adults & adolescents: 100–200mcg twice daily (1–2 puffs)
2. Children 4–11 years: 100mcg twice daily (1 puff)
3. Maximum daily dose: 400mcg (4 puffs) unless under specialist supervision

Who It’s For (XALTIDE HFA 100 MDI):

1. Adults and children (≥4 years) with mild to moderate persistent asthma
2. Patients stepping up from short-acting beta-agonists alone
3. Those requiring low-dose inhaled corticosteroid therapy

Warnings & Precautions:

1. Not a rescue inhaler—use only for maintenance
2. Monitor growth in children on long-term therapy
3. Screen for tuberculosis, ocular herpes, or osteoporosis before/long-term use
4. Taper gradually if discontinuing after prolonged high-dose use

Drug Interactions:

1. Strong CYP3A4 inhibitors (ketoconazole, ritonavir): May increase systemic fluticasone levels—risk of Cushing’s syndrome or adrenal suppression
2. Always inform your doctor about all medications.

Additional Information:

Store below 30°C. Do not puncture, freeze, or expose to heat >50°C. Keep out of reach of children. Clean inhaler mouthpiece weekly. Available by prescription in Pakistan.