Product Information:

AMCLAV 625mg Tablets contain a synergistic combination of Amoxicillin (500mg) and Clavulanic Acid (125mg), providing broad-spectrum antibacterial coverage against both susceptible and beta-lactamase-producing resistant bacteria. This formulation is widely used for moderate bacterial infections in adults and adolescents, offering enhanced efficacy compared to amoxicillin alone by protecting it from enzymatic degradation.

Uses of (AMCLAV 625MG TABLETS):

AMCLAV 625mg Tablets are indicated for the treatment of respiratory tract infections (e.g., sinusitis, bronchitis, pneumonia), urinary tract infections (UTIs), skin and soft tissue infections, otitis media, dental abscesses, and bone/joint infections caused by susceptible organisms. It is particularly effective in recurrent or community-acquired infections where resistance is suspected.

Key Benefits of (AMCLAV 625MG TABLETS):

1. Effective against common resistant pathogens
2. Balanced strength for moderate infections
3. Twice-daily dosing improves adherence
4. Rapid absorption and high tissue penetration
5. Well-tolerated with established clinical safety

How To Use (AMCLAV 625MG TABLETS):

Take one tablet every 12 hours (twice daily) with food to reduce gastrointestinal irritation. Swallow whole with water—do not crush or chew. Complete the full prescribed course, even if symptoms improve early, to prevent relapse and antibiotic resistance.

When Not to Use (AMCLAV 625MG TABLETS):

Do not use if you have a known allergy to penicillins, cephalosporins, or clavulanic acid. Avoid in patients with a history of amoxicillin/clavulanate-associated cholestatic jaundice or severe liver dysfunction. Contraindicated in infectious mononucleosis due to high risk of rash.

Side Effects of (AMCLAV 625MG TABLETS):

Common: Diarrhea, nausea, vomiting, abdominal discomfort, and mild skin rash.

Rare but serious: Allergic reactions (anaphylaxis), Clostridioides difficile-associated colitis, hepatitis, jaundice, or severe cutaneous reactions. Discontinue immediately and seek medical help if yellowing of eyes/skin, persistent watery stools, or breathing difficulty occurs.

Dosage: (AMCLAV 625MG TABLETS):

Standard adult dose: One tablet (500mg/125mg) twice daily for 5–14 days, depending on infection severity. In renal impairment (CrCl <30 mL/min), reduce to once daily. Always follow your physician’s prescription.

Who It’s For (AMCLAV 625MG TABLETS):

Designed for adults and adolescents (≥12 years and ≥40 kg) with moderate bacterial infections requiring reliable, broad-spectrum coverage. Not suitable for children under 12 or those needing lower-strength formulations.

Warnings & Precautions:

Use cautiously in patients with renal or hepatic impairment, asthma, or history of allergies. Prolonged therapy may lead to fungal overgrowth or antibiotic-associated diarrhea. Monitor for signs of superinfection. Inform your doctor if pregnant, breastfeeding, or have gastrointestinal disease.

Drug Interactions:

May reduce effectiveness of oral contraceptives. Increases risk of methotrexate toxicity. Co-administration with allopurinol raises rash incidence. Probenecid can elevate amoxicillin levels. Always disclose all medications to your healthcare provider.

Additional Information:

Store below 25°C in a dry place, away from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the blister pack. Available by prescription only in Pakistan.