Product Information:

VILANTO-F 200 + 25mcg is a fixed-dose combination dry powder inhaler (DPI) containing:

1. Indacaterol Acetate 200mcg – a long-acting beta₂-agonist (LABA) that provides sustained 24-hour bronchodilation
2. Mometasone Furoate 25mcg – an inhaled corticosteroid (ICS) that reduces airway inflammation and hyperresponsiveness

This higher-strength dual-combination therapy is indicated for the maintenance treatment of moderate to severe persistent asthma in adults and adolescents (≥12 years) who are not adequately controlled on lower-strength ICS/LABA combinations or require intensified anti-inflammatory and bronchodilator therapy.

⚠️ Important Safety Note:

LABAs (like indacaterol) increase the risk of asthma-related death when used without an inhaled corticosteroid. This product includes both, making it appropriate for maintenance—but never use as monotherapy or for acute attacks.

Uses of (VILANTO-F 200 + 25MCG):

1. Maintenance treatment of moderate to severe persistent asthma
2. Patients uncontrolled on lower-dose ICS/LABA (e.g., 100/25 mcg)
3. Long-term control of wheezing, dyspnea, chest tightness, and chronic cough

Key Benefits of (VILANTO-F 200 + 25MCG):

1. Enhanced bronchodilation with 200mcg indacaterol for better symptom control
2. Anti-inflammatory action from mometasone 25mcg to reduce exacerbations
3. Once-daily dosing for consistent 24-hour coverage
4. Improved lung function (FEV₁) and quality of life

How To Use (VILANTO-F 200 + 25MCG):

1. Insert one capsule into the compatible DPI device (e.g., Breezhaler®).
2. Pierce the capsule and inhale quickly and deeply through the mouthpiece.
3. Hold breath for 5–10 seconds, then exhale gently.
4. Dosage: One capsule once daily at the same time each day.
5. Rinse mouth thoroughly with water after each use to prevent oral thrush and hoarseness.
6. Not for acute bronchospasm—always carry a short-acting rescue inhaler (e.g., salbutamol).

🚫 Do not swallow the capsule—for inhalation only.

When Not to Use (VILANTO-F 200 + 25MCG):

Do not use if you have:

1. Hypersensitivity to indacaterol, mometasone, or any excipients
2. Acute asthma attack, status asthmaticus, or rapidly deteriorating asthma
3. Primary treatment of exercise-induced bronchospasm alone

Side Effects of (VILANTO-F 200 + 25MCG):

Common:

1. Headache, throat irritation
2. Oral candidiasis (thrush)—reduced by rinsing mouth
3. Hoarseness, cough
4. Tremor or palpitations (from higher indacaterol dose)

Less common:

1. Easy bruising, adrenal suppression (with long-term ICS use)
2. Muscle cramps, dizziness

Serious (rare):

1. Paradoxical bronchospasm—discontinue immediately if breathing worsens
2. Glaucoma or cataracts (with prolonged high-dose ICS)
3. Adrenal insufficiency (if stopped abruptly after long-term use)
4. Seek medical help if vision changes, worsening respiratory symptoms, or signs of systemic steroid effects occur.

Dosage: (VILANTO-F 200 + 25MCG):

1. Adults & adolescents ≥12 years: One capsule once daily
2. Maximum: One capsule per 24 hours
3. Not for children <12 years
4. Do not exceed recommended dose

Who It’s For (VILANTO-F 200 + 25MCG):

Adults and adolescents with moderate to severe persistent asthma requiring intensified dual therapy beyond standard ICS/LABA doses.

Warnings & Precautions:

1. Not a rescue medication—use only for maintenance
2. Monitor growth in adolescents on long-term therapy
3. Screen for tuberculosis, ocular herpes, or osteoporosis before initiating or during prolonged use
4. Taper gradually if discontinuing after extended therapy

Drug Interactions:

1. Strong CYP3A4 inhibitors (ketoconazole, ritonavir): May increase systemic exposure to mometasone—risk of Cushing’s syndrome
2. Beta-blockers: May antagonize indacaterol and induce bronchospasm
3. Always inform your doctor about all medications and supplements.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep capsules in original blister until use. Do not use after the expiration date. Available by prescription only in Pakistan.