Product Information:

TARLYCA 2.5mg Tablets contain Tadalafil 2.5mg, a phosphodiesterase type 5 (PDE5) inhibitor. It works by enhancing the effects of nitric oxide in the corpus cavernosum of the penis, promoting smooth muscle relaxation and increased blood flow, which facilitates erections in response to sexual stimulation.

The 2.5mg dose is specifically designed for once-daily use in the treatment of erectile dysfunction (ED) and/or benign prostatic hyperplasia (BPH).

Uses of (TARLYCA 2.5MG TABS):

1. Erectile dysfunction (ED) – as a low-dose daily regimen for spontaneous sexual activity
2. Benign prostatic hyperplasia (BPH) – to improve urinary symptoms (hesitancy, weak stream, nocturia)
3. Combined ED + BPH – when both conditions coexist

Key Benefits of (TARLYCA 2.5MG TABS):

1. Once-daily dosing enables spontaneous sexual activity (no need for timing with intercourse)
2. Lower incidence of side effects compared to on-demand higher doses (e.g., 10mg or 20mg)
3. Dual benefit for men with both ED and BPH
4. Long half-life (~17.5 hours) supports consistent therapeutic levels

How To Use (TARLYCA 2.5MG TABS):

1. Take once daily, at approximately the same time each day, with or without food.
2. Swallow whole with water—do not crush or chew.
3. Sexual stimulation is still required for an erection to occur.
4. May take several days to achieve steady-state levels for full effect.

When Not to Use (TARLYCA 2.5MG TABS):

Do not use if you have:

1. Hypersensitivity to tadalafil or any excipients
2. Concurrent use of nitrates (e.g., nitroglycerin, isosorbide) or guanylate cyclase stimulators (e.g., riociguat)—risk of life-threatening hypotension
3. Severe cardiovascular disease (e.g., recent MI, stroke, unstable angina, uncontrolled arrhythmia)
4. Severe hepatic impairment or end-stage renal disease on dialysis

⚠️ Important: Do not combine with other PDE5 inhibitors (e.g., sildenafil, vardenafil).

Side Effects of (TARLYCA 2.5MG TABS):

Common (mild and less frequent at 2.5mg):

1. Headache
2. Indigestion, back pain
3. Nasal congestion, flushing
4. Muscle aches

Less common:

1. Dizziness, blurred vision
2. Prolonged erection (priapism—seek help if >4 hours)

Serious (rare):

1. Sudden hearing or vision loss (NAION)—discontinue immediately
2. Cardiovascular events (chest pain, arrhythmia)—especially in high-risk patients
3. Hypotension (if combined with nitrates or alpha-blockers)
4. Seek emergency care if chest pain, sudden vision/hearing changes, or prolonged erection occurs.

Dosage: (TARLYCA 2.5MG TABS):

1. Adults: 2.5mg once daily
2. May increase to 5mg once daily based on efficacy and tolerability
3. Maximum: 5mg/day for daily use

Who It’s For (TARLYCA 2.5MG TABS):

Men with erectile dysfunction who prefer daily dosing for spontaneity, or those with BPH, especially when both conditions are present.

Warnings & Precautions:

1. Avoid alcohol excess—may enhance hypotensive effects
2. Use caution with alpha-blockers (e.g., tamsulosin)—risk of orthostatic hypotension
3. Evaluate cardiovascular status before initiation in men with cardiac risk factors
4. Discontinue if signs of NAION (non-arteritic anterior ischemic optic neuropathy) occur

Drug Interactions:

1. Nitrates: Contraindicated—severe hypotension
2. Alpha-blockers: ↑ Risk of dizziness, syncope
3. CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): May increase tadalafil levels—use lower dose
4. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Available by prescription in Pakistan.