Product Information:

TALFIL 20mg Tablets contain Tadalafil 20mg, a phosphodiesterase type 5 (PDE5) inhibitor. It enhances the effects of nitric oxide in the corpus cavernosum, promoting smooth muscle relaxation and increased blood flow to facilitate erections in response to sexual stimulation.

The 20mg dose is the maximum approved on-demand strength for erectile dysfunction (ED), used when lower doses (e.g., 10mg) are insufficient.

Uses of (TALFIL 20MG TAB):

1. Erectile dysfunction (ED) – as an on-demand oral therapy
2. Not indicated for daily use or benign prostatic hyperplasia (BPH)—lower doses (2.5–5mg) are used for those indications

Key Benefits of (TALFIL 20MG TAB):

1. Effective within 30–60 minutes of intake
2. Longest duration of action among PDE5 inhibitors—up to 36 hours (“weekend pill”)
3. Flexible, as-needed dosing
4. Proven efficacy in men with diabetes, post-prostatectomy, or severe ED

How To Use (TALFIL 20MG TAB):

1. Take as needed, 30–60 minutes before sexual activity.
2. Swallow whole with water—can be taken with or without food (high-fat meals may delay onset).
3. Do not take more than once per day.
4. Sexual stimulation is required for an erection to occur.

💡 Note: 20mg is the maximum recommended dose. Do not exceed once daily.

When Not to Use (TALFIL 20MG TAB):

Do not use if you have:

1. Hypersensitivity to tadalafil or any excipients
2. Concurrent use of nitrates (e.g., nitroglycerin, isosorbide) or guanylate cyclase stimulators (e.g., riociguat)—risk of life-threatening hypotension
3. Severe cardiovascular disease (unstable angina, recent MI/stroke, uncontrolled arrhythmia)
4. Severe hepatic impairment (Child-Pugh Class C) or end-stage renal disease on dialysis

⚠️ Important: Do not combine with other PDE5 inhibitors (e.g., sildenafil, vardenafil).

Side Effects of (TALFIL 20MG TAB):

Common (more frequent at 20mg):

1. Headache
2. Indigestion, back pain
3. Nasal congestion, flushing
4. Muscle aches, dizziness

Less common:

1. Blurred vision, eye redness
2. Prolonged erection (priapism—seek emergency care if >4 hours)

Serious (rare):

1. Sudden hearing or vision loss (NAION)—discontinue immediately
2. Cardiovascular events (chest pain, arrhythmia)—especially in high-risk patients
3. Severe hypotension (if combined with nitrates or alpha-blockers)
4. Seek emergency help if chest pain, sudden vision/hearing changes, or prolonged erection occurs.

Dosage: (TALFIL 20MG TAB):

1. Maximum on-demand dose: 20mg as needed, prior to sexual activity
2. Frequency: Once per day maximum
3. Only use if 10mg is insufficient and well-tolerated

Who It’s For (TALFIL 20MG TAB):

Men with moderate to severe erectile dysfunction who have not achieved satisfactory results with 10mg tadalafil and are otherwise medically fit for sexual activity.

Warnings & Precautions:

1. Avoid excessive alcohol—may worsen hypotension or dizziness
2. Use caution in patients with anatomical penile deformity (e.g., Peyronie’s disease) or bleeding disorders
3. Evaluate cardiovascular health before initiation in men with cardiac risk factors
4. Discontinue if signs of non-arteritic anterior ischemic optic neuropathy (NAION) occur

Drug Interactions:

1. Nitrates: Contraindicated—severe, potentially fatal hypotension
2. Alpha-blockers: May cause significant blood pressure drop—start with lower tadalafil dose if co-administered
3. Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): May increase tadalafil levels—consider 10mg max
4. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Available by prescription in Pakistan