Product Information:

SAVESTO 50mg (24mg + 26mg) Tablets contain a fixed-dose combination of:

1. Diosmin 24mg
2. Hesperidin 26mg

Together, these citrus bioflavonoids form a micronized purified flavonoid fraction (MPFF) totaling 50mg per tablet. This low-dose formulation supports venous and lymphatic function by improving venous tone, reducing capillary permeability, and decreasing inflammation.

It is typically used for mild chronic venous symptoms, pediatric dosing (off-label), or as a maintenance therapy in patients requiring gentle, long-term vascular support.

Uses of (SAVESTO 50MG 24MG+26MG TABLETS):

1. Relief of mild symptoms of chronic venous insufficiency (leg heaviness, tiredness, tingling, mild swelling)
2. Adjunctive management of chronic hemorrhoids
3. Support in early-stage varicose veins or post-procedural care
4. Prevention of symptom recurrence after acute treatment

Key Benefits of (SAVESTO 50MG 24MG+26MG TABLETS):

1. Enhances venous return and reduces venous stasis
2. Decreases capillary fragility and edema
3. Well-tolerated with minimal side effects
4. Suitable for long-term use due to low systemic absorption

How To Use (SAVESTO 50MG 24MG+26MG TABLETS):

1. Take as prescribed by your physician.
2. Typical adult dosage: 1–2 tablets twice daily with meals.
3. For children (if used off-label): Dosing based on weight—consult a pediatrician.
4. Swallow whole with water—do not crush or chew.
5. Use consistently for optimal results; effects may take several weeks.

When Not to Use (SAVESTO 50MG 24MG+26MG TABLETS):

Do not use if you have:

1. Hypersensitivity to diosmin, hesperidin, or citrus bioflavonoids
2. Known allergy to any excipients in the tablet
3. Active gastrointestinal bleeding or severe liver disease (use with caution)

Side Effects of (SAVESTO 50MG 24MG+26MG TABLETS):

Common: Mild gastrointestinal upset (nausea, abdominal discomfort).

Rare: Headache, dizziness, skin rash.

Serious (very rare): Allergic reactions (urticaria, facial swelling).

Discontinue and seek medical help if signs of hypersensitivity occur.

Dosage: (SAVESTO 50MG 24MG+26MG TABLETS):

1. Adults: 1–2 tablets twice daily (total 50–100mg/day)
2. Duration: Weeks to months, depending on condition severity
3. Children: Not officially indicated; use only under specialist supervision

Who It’s For (SAVESTO 50MG 24MG+26MG TABLETS):

1. Adults with mild venous symptoms (e.g., leg fatigue, minor swelling)
2. Elderly patients needing gentle vascular support
3. Individuals on long-term maintenance after higher-dose therapy
4. Those seeking preventive care for venous health

Warnings & Precautions:

1. Not a substitute for compression stockings, exercise, or leg elevation
2. Rule out deep vein thrombosis (DVT) before treating leg swelling
3. Use cautiously in pregnancy—limited data, though flavonoids are generally low-risk
4. Discontinue 1–2 weeks before surgery (theoretical bleeding risk)

Drug Interactions:

1. Low interaction potential due to minimal systemic absorption
2. Theoretical interaction with anticoagulants (e.g., warfarin)—monitor INR if combined
3. Always inform your doctor about all medications and supplements.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date. Available over-the-counter in Pakistan.