Product Information:

RUPATAGET 10mg Tablets contain Rupatadine Fumarate 10mg, a second-generation antihistamine with dual action as a selective histamine H₁-receptor antagonist and platelet-activating factor (PAF) inhibitor. This unique mechanism provides enhanced relief in allergic conditions by targeting both histamine and PAF-mediated inflammation.

It is used for the symptomatic treatment of allergic rhinitis and chronic urticaria (hives) in adults and adolescents.

Uses of (RUPATAGET 10MG TABLETS):

1. Relief of symptoms of seasonal and perennial allergic rhinitis (sneezing, runny nose, itchy/watery eyes, nasal congestion)
2. Treatment of chronic idiopathic urticaria (persistent hives without known cause)
3. Management of allergic conjunctivitis (as part of systemic therapy)

Key Benefits of (RUPATAGET 10MG TABLETS):

1. Dual inhibition of histamine + PAF—more effective than standard antihistamines in some patients
2. Non-sedating at recommended doses (minimal CNS penetration)
3. Once-daily dosing for 24-hour symptom control
4. Rapid onset of action (within 1–2 hours)

How To Use (RUPATAGET 10MG TABLETS):

1. Take one tablet (10mg) once daily, with or without food.
2. Swallow whole with water—do not crush or chew.
3. For best results, take regularly during allergy season or as prescribed.
4. May be taken long-term under medical supervision for chronic urticaria.

When Not to Use (RUPATAGET 10MG TABLETS):

Do not use if you have:

1. Hypersensitivity to rupatadine or any excipients
2. Severe hepatic impairment
3. History of QT prolongation or cardiac arrhythmias
4. Concurrent use of strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) in patients with cardiac risk

⚠️ Note: Although generally non-sedating, caution is advised when operating machinery until individual response is known.

Side Effects of (RUPATAGET 10MG TABLETS):

Common: Headache, drowsiness (mild), dry mouth, fatigue.

Less common: Dizziness, nausea, abdominal pain.

Serious (rare):

1. QT prolongation (in overdose or high-risk individuals)
2. Severe hypersensitivity reactions (angioedema, anaphylaxis)
3. Discontinue and seek help if rash, swelling, or breathing difficulty occurs.

Dosage: (RUPATAGET 10MG TABLETS):

1. Adults & adolescents (≥12 years): 10mg once daily
2. Elderly or mild hepatic impairment: No dose adjustment needed
3. Severe liver disease: Avoid or use with extreme caution
4. Children <12 years: Not recommended

Who It’s For (RUPATAGET 10MG TABLETS):

Adults and adolescents (≥12 years) suffering from moderate to severe allergic rhinitis or chronic urticaria who require effective, once-daily, non-sedating relief.

Warnings & Precautions:

1. Avoid alcohol—may enhance drowsiness
2. Use cautiously in elderly patients with cardiovascular disease
3. Discontinue 48 hours before skin allergy testing (may suppress skin reactivity)
4. Not for acute asthma or anaphylaxis

Drug Interactions:

1. Strong CYP3A4 inhibitors (ketoconazole, clarithromycin, erythromycin): May ↑ rupatadine levels—use with caution
2. CNS depressants (alcohol, benzodiazepines): May ↑ sedation
3. QT-prolonging drugs: Theoretical risk—avoid in high-risk patients
4. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date. Available over-the-counter or by prescription in Pakistan.