Product Information:

ORLIFIT 120mg Capsules contain Orlistat 120mg, a gastrointestinal lipase inhibitor used as an adjunct to weight-loss therapy in overweight and obese adults. Orlistat works by blocking the action of gastric and pancreatic lipases, enzymes that break down dietary fats in the gut. This prevents the absorption of approximately 30% of ingested fat, which is then excreted unchanged in the stool.

It is intended for use alongside a reduced-calorie, low-fat diet and increased physical activity.

⚠️ Note: ORLIFIT 120mg is the prescription-strength formulation (vs. 60mg OTC versions like Alli®).

Uses of (ORLIFIT 120MG CAPSULES):

1. Weight management in adults with BMI ≥30 kg/m² (obese)
2. Weight control in overweight adults (BMI ≥27 kg/m²) with risk factors (e.g., hypertension, diabetes, dyslipidemia)
3. Prevention of weight regain after prior weight loss

Key Benefits of (ORLIFIT 120MG CAPSULES):

1. Promotes clinically significant weight loss (5–10% of body weight over 6–12 months)
2. Improves lipid profile, glycemic control, and blood pressure
3. Acts locally in the gut—minimal systemic absorption
4. Non-stimulant mechanism—no cardiovascular or CNS side effects

How To Use (ORLIFIT 120MG CAPSULES):

1. Take one capsule (120mg) three times daily with each main meal containing fat.
2. Take during or up to 1 hour after the meal.
3. If a meal is missed or contains no fat, skip the dose.
4. Follow a balanced, reduced-calorie diet with ≤30% of calories from fat.
5. Take a multivitamin supplement (containing A, D, E, K) at least 2 hours before or after ORLIFIT (or at bedtime), as orlistat may reduce fat-soluble vitamin absorption.

When Not to Use (ORLIFIT 120MG CAPSULES):

Do not use if you have:

1. Chronic malabsorption syndrome (e.g., Crohn’s disease)
2. Cholestasis or gallbladder disease
3. Hypersensitivity to orlistat
4. Pregnancy or breastfeeding

Side Effects of (ORLIFIT 120MG CAPSULES):

Common (related to undigested fat):

1. Oily spotting, flatus with discharge
2. Fecal urgency, oily/fatty stools
3. Increased bowel movements, abdominal discomfort

These effects are dose-dependent and decrease with lower dietary fat intake.

Rare/Serious:

1. Severe liver injury (rare post-marketing reports—discontinue if jaundice, dark urine, or fatigue occurs)
2. Kidney stones (due to increased oxalate absorption)
3. Vitamin deficiencies (with long-term use without supplementation)

Dosage: (ORLIFIT 120MG CAPSULES):

1. Adults: 120mg three times daily with meals
2. Maximum: 360mg per day
3. Duration: Up to 1–2 years under medical supervision
4. Discontinue if no weight loss after 12 weeks

Who It’s For (ORLIFIT 120MG CAPSULES):

Overweight or obese adults committed to lifestyle changes who need pharmacological support for weight loss.

Warnings & Precautions:

1. Requires strict adherence to a low-fat diet to minimize GI side effects
2. May interfere with absorption of fat-soluble vitamins and some medications (e.g., levothyroxine, cyclosporine)—dose timing must be separated
3. Not a substitute for diet and exercise
4. Monitor liver function if symptoms of hepatotoxicity appear

Drug Interactions:

1. Fat-soluble vitamins (A, D, E, K): Reduced absorption—supplement separately
2. Levothyroxine: Reduced absorption—administer 4+ hours apart
3. Cyclosporine, amiodarone: Reduced levels—monitor closely
4. Always inform your doctor about all medications and supplements.

Additional Information:

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children. Available by prescription in Pakistan.