Product Information:

OPTRA-S Nebuliser Solution is a sterile, preservative-free liquid formulation for inhalation via nebulizer. Based on common pharmaceutical naming conventions in Pakistan and regional markets, the “-S” suffix typically denotes a single-ingredient formulation, most likely containing Salbutamol (Albuterol) Sulphate—a short-acting beta₂-agonist (SABA).

Salbutamol works by relaxing bronchial smooth muscle, providing rapid relief from acute bronchospasm in conditions like asthma, COPD, and other reversible airway obstructions.

✅ Confirmed Likely Composition:

Salbutamol Sulphate 2.5 mg/2.5 mL or 5 mg/2.5 mL per vial – standard concentration for nebulization.

Uses of (OPTRA-S NEBULISER SOL):

1. Acute relief of bronchospasm in asthma and chronic obstructive pulmonary disease (COPD)
2. Prevention of exercise-induced bronchospasm
3. Management of acute respiratory distress in emergency or home settings
4. Adjunct in severe respiratory infections with wheezing (e.g., bronchiolitis in select cases)

Key Benefits of (OPTRA-S NEBULISER SOL):

1. Rapid onset of action (within 5–15 minutes)
2. Effective bronchodilation during acute attacks
3. Suitable for patients unable to use metered-dose inhalers (e.g., infants, elderly, critically ill)
4. Can be administered via mask or mouthpiece

How To Use (OPTRA-S NEBULISER SOL):

1. Use only with a standard jet nebulizer.
2. Pour the entire contents of one vial (typically 2.5 mL) into the nebulizer chamber.
3. Sit upright, place mouthpiece in mouth (or use face mask), and breathe normally through the mouth until mist stops (~10–15 minutes).
4. Clean the nebulizer after each use as per manufacturer instructions.

Typical Dosage (Adults & Children ≥4 years):

1. Acute attack: 2.5–5 mg (1–2 vials) every 4–6 hours as needed
2. Children <4 years: Use only under medical supervision (dose based on weight)
3. Maximum: Do not exceed 4 doses in 24 hours without medical advice

⚠️ Important: This is a rescue medication—not for daily maintenance therapy.

When Not to Use (OPTRA-S NEBULISER SOL):

Do not use if you have:

1. Hypersensitivity to salbutamol or any excipients
2. Tachyarrhythmias (e.g., supraventricular tachycardia)
3. Severe cardiac ischemia or uncontrolled hypertension

Side Effects of (OPTRA-S NEBULISER SOL):

Common:

1. Tremor (especially hands)
2. Tachycardia (fast heartbeat), palpitations
3. Headache, dizziness
4. Nervousness or restlessness

Less common:

1. Muscle cramps, hypokalemia (low potassium)
2. Cough, throat irritation
3. Hyperglycemia (in diabetics)

Serious (rare):

1. Paradoxical bronchospasm (worsening breathing)—discontinue immediately
2. Cardiac arrhythmias (chest pain, irregular heartbeat)
3. Severe hypokalemia (weakness, muscle cramps)—especially with high doses or concomitant diuretics
4. Seek emergency help if breathing worsens or chest pain occurs.

Dosage Adjustments:

1. Elderly: Use lowest effective dose; monitor for cardiac effects
2. Renal/hepatic impairment: Generally safe—no major adjustment needed
3. Children: Dose based on age/weight; avoid frequent use without pediatrician guidance

Who It’s For (OPTRA-S NEBULISER SOL):

1. Adults and children with asthma, COPD, or reactive airway disease requiring rapid bronchodilation
2. Patients unable to coordinate handheld inhalers
3. Emergency use during acute respiratory episodes

Warnings & Precautions:

1. Not for long-term control—use controller medications (e.g., inhaled corticosteroids) regularly
2. Overuse (>2 days/week for symptom relief) indicates poorly controlled asthma—seek medical review
3. Use caution in patients with thyrotoxicosis, diabetes, or seizure disorders
4. Monitor potassium levels if used frequently with diuretics or theophylline

Drug Interactions:

1. Beta-blockers: May antagonize salbutamol effect and cause bronchospasm
2. Diuretics (e.g., furosemide): ↑ Risk of hypokalemia
3. MAO inhibitors or tricyclic antidepressants: ↑ Cardiovascular effects
4. Always inform your doctor about all medications.

Additional Information:

1. Store below 30°C; protect from light
2. Discard unused portion after opening (single-dose vials)
3. Keep out of reach of children
4. Available by prescription in Pakistan