Product Information:

MIBEGA 25mg Tablets contain Miglitol 25mg, an alpha-glucosidase inhibitor used as an oral antidiabetic agent in the management of type 2 diabetes mellitus. Miglitol works by competitively inhibiting alpha-glucosidase enzymes in the small intestine, which delays the digestion and absorption of carbohydrates. This results in a reduction of postprandial (after-meal) blood glucose spikes.

It is typically used as an adjunct to diet and exercise, and may be combined with other antidiabetic agents like metformin or insulin.

Uses of (MIBEGA 25MG TABLETS):

1. Monotherapy in adults with type 2 diabetes not controlled by diet and exercise alone
2. Combination therapy with metformin, sulfonylureas, or insulin
3. Management of postprandial hyperglycemia (high blood sugar after meals)

Key Benefits of (MIBEGA 25MG TABLETS):

1. Specifically targets post-meal blood glucose spikes
2. Does not cause hypoglycemia when used alone
3. Weight-neutral (does not cause weight gain)
4. May improve glycemic variability and HbA1c modestly

How To Use (MIBEGA 25MG TABLETS):

1. Take three times daily, with the first bite of each main meal.
2. Swallow whole with water—do not crush or chew.
3. Must be taken with meals containing complex carbohydrates to be effective.
4. If a meal is skipped, skip the corresponding dose.

When Not to Use (MIBEGA 25MG TABLETS):

Do not use if you have:

1. Diabetic ketoacidosis
2. Inflammatory bowel disease (e.g., Crohn’s disease, ulcerative colitis)
3. Chronic intestinal diseases associated with marked disorders of digestion or absorption
4. Conditions that may worsen with increased gas production (e.g., hernias, intestinal obstruction)
5. Hypersensitivity to miglitol or any excipients

Side Effects of (MIBEGA 25MG TABLETS):

Common: Flatulence (gas), diarrhea, abdominal pain, bloating—due to undigested carbohydrates fermenting in the colon.

Rare: Skin rash, low serum iron.

Serious (rare):

1. Hypoglycemia (only when combined with insulin or sulfonylureas—treat with glucose, not sucrose)
2. Discontinue if severe gastrointestinal discomfort persists.

Dosage: (MIBEGA 25MG TABLETS):

1. Starting dose: 25mg three times daily with meals
2. May be increased gradually to 50mg or 100mg three times daily based on response and tolerability
3. Maximum dose: 100mg three times daily
4. Elderly or renal impairment: Start at 25mg; avoid higher doses if CrCl <25 mL/min

Who It’s For (MIBEGA 25MG TABLETS):

Adults with type 2 diabetes who experience significant postprandial hyperglycemia and can tolerate gastrointestinal side effects. Not suitable for patients with frequent gastrointestinal disorders.

Warnings & Precautions:

1. Gastrointestinal side effects often decrease over time—start with low dose
2. In case of hypoglycemia (when combined with other agents), treat with glucose (dextrose)—not table sugar (sucrose)—as miglitol blocks sucrose breakdown
3. Avoid high-sucrose diets to reduce gas and bloating
4. Monitor HbA1c every 3 months

Drug Interactions:

1. Digestive enzyme supplements (e.g., amylase, pancreatin): May reduce miglitol efficacy
2. Charcoal or adsorbent antacids: May decrease absorption
3. Sulfonylureas/insulin: ↑ Risk of hypoglycemia
4. Always inform your doctor about all medications and supplements.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date. Available by prescription in Pakistan.