Product Information:

MEBEVER MR 200mg Capsules contain Mebeverine Hydrochloride 200mg in a Modified-Release (MR) formulation. Mebeverine is an antispasmodic agent that acts directly on smooth muscle in the gastrointestinal tract, reducing spasms and cramping without anticholinergic side effects. The MR formulation ensures gradual release over several hours, providing prolonged symptom relief.

Uses of (MEBEVER MR 200MG CAPSULES):

1. Symptomatic treatment of Irritable Bowel Syndrome (IBS) (abdominal pain, bloating, cramps, diarrhea/constipation)
2. Relief of functional gastrointestinal disorders with spasm-related pain
3. Management of intestinal colic and spastic constipation

Key Benefits of (MEBEVER MR 200MG CAPSULES):

1. No anticholinergic effects—does not cause dry mouth, blurred vision, or urinary retention
2. Modified-release action provides sustained relief for up to 12 hours
3. Once- or twice-daily dosing improves adherence
4. Safe for long-term use in chronic IBS

How To Use (MEBEVER MR 200MG CAPSULES):

1. Take one capsule twice daily, approximately 20 minutes before breakfast and dinner.
2. Swallow whole with water—do not crush, chew, or open (to preserve modified-release mechanism).
3. May be taken with or without food, but consistent timing enhances efficacy.
4. Continue during symptomatic periods; may be used intermittently or continuously.

When Not to Use (MEBEVER MR 200MG CAPSULES):

Do not use if you have:

1. Hypersensitivity to mebeverine or any excipients
2. Paralytic ileus or intestinal obstruction
3. Severe inflammatory bowel disease (e.g., active ulcerative colitis, Crohn’s disease)
4. Uninvestigated rectal bleeding or significant weight loss (rule out organic disease first)

Side Effects of (MEBEVER MR 200MG CAPSULES):

Generally well-tolerated. Rare side effects may include:

1. Mild dizziness, headache, or fatigue
2. Nausea, heartburn, or mild skin rash
3. Very rare: Allergic reactions (urticaria, facial swelling)
4. Discontinue if hypersensitivity occurs.

Dosage: (MEBEVER MR 200MG CAPSULES):

1. Adults & adolescents ≥12 years: 200mg twice daily (before morning and evening meals)
2. Elderly: No dose adjustment needed
3. Children <12 years: Not recommended
4. Duration: As needed for symptom control; safe for long-term use under medical guidance

Who It’s For (MEBEVER MR 200MG CAPSULES):

Adults and adolescents with diagnosed irritable bowel syndrome (IBS) or functional gut disorders characterized by abdominal cramping and altered bowel habits.

Warnings & Precautions:

1. Use only after organic causes (e.g., infection, inflammation, malignancy) are ruled out
2. Not effective in inflammatory bowel disease (IBD)—may mask symptoms
3. Does not impair driving or machinery operation (non-sedating)
4. Safe in patients with glaucoma or prostate enlargement (no anticholinergic activity)

Drug Interactions:

1. No significant drug interactions reported
2. May be safely combined with probiotics, fiber supplements, or other IBS therapies
3. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date. Available over-the-counter in Pakistan.