Product Information:

LIPIGET 10mg Tablets contain Atorvastatin 10mg, a statin-class lipid-lowering agent. Atorvastatin works by inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis in the liver. This leads to reduced production of LDL ("bad") cholesterol and triglycerides, while modestly increasing HDL ("good") cholesterol.

This low-to-moderate strength is commonly used for primary prevention or as a starting dose in patients with mild to moderate hyperlipidemia.

Uses of (LIPIGET 10MG TABLETS):

1. Primary hyperlipidemia (elevated LDL cholesterol)
2. Mixed dyslipidemia (Fredrickson Type IIa and IIb)
3. Prevention of cardiovascular events in patients with risk factors (e.g., hypertension, diabetes, smoking)
4. Adjunct to diet and lifestyle modifications in adults and children ≥10 years

Key Benefits of (LIPIGET 10MG TABLETS):

1. Reduces LDL cholesterol by 30–40% at this dose
2. Lowers risk of heart attack, stroke, and revascularization procedures
3. Once-daily dosing for improved adherence
4. Well-tolerated starting dose with lower risk of muscle-related side effects

How To Use (LIPIGET 10MG TABLETS):

1. Take one tablet once daily, with or without food, at the same time each day.
2. Swallow whole with water—do not crush or chew.
3. Continue a heart-healthy diet, regular exercise, and weight management.
4. Monitor lipid profile and liver enzymes as directed by your doctor.

When Not to Use (LIPIGET 10MG TABLETS):

Do not use if you have:

1. Active liver disease or unexplained persistent elevations in liver enzymes
2. Hypersensitivity to atorvastatin or any excipients
3. Pregnancy or breastfeeding (may cause fetal harm)

Side Effects of (LIPIGET 10MG TABLETS):

Common: Headache, diarrhea, abdominal pain, muscle aches, fatigue, nausea.

Rare: Elevated liver enzymes, joint pain, insomnia.

Serious (rare):

1. Myopathy/rhabdomyolysis (unexplained muscle pain, weakness, dark urine)
2. Hepatotoxicity (jaundice, dark urine, right upper quadrant pain)
3. Discontinue and seek medical help if severe symptoms occur.

Dosage: (LIPIGET 10MG TABLETS):

1. Adults: 10mg once daily (starting dose); may be increased to 20–80mg based on response
2. Children (10–17 years): 10mg once daily (max 20mg/day)
3. Elderly or renal impairment: No dose adjustment needed, but monitor closely

Who It’s For (LIPIGET 10MG TABLETS):

Adults and adolescents (≥10 years) with mild to moderate hypercholesterolemia or those initiating statin therapy for cardiovascular risk reduction.

Warnings & Precautions:

1. Check liver function tests before starting and as clinically indicated
2. Report unexplained muscle pain or weakness immediately
3. Avoid grapefruit juice in large quantities (may increase drug levels)
4. Use caution in patients with hypothyroidism, renal impairment, or history of muscle disorders

Drug Interactions:

1. Strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, HIV protease inhibitors): ↑ Risk of myopathy
2. Cyclosporine, fibrates: ↑ Risk of muscle toxicity
3. Warfarin: May enhance anticoagulant effect—monitor INR
4. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date on the blister pack. Available by prescription in Pakistan.