Product Information:

LARINEX 5mg Tablets contain Levocetirizine Dihydrochloride 5mg, a third-generation antihistamine and the active enantiomer of cetirizine. It is a potent, selective peripheral H1-receptor antagonist that provides rapid and long-lasting relief from allergic symptoms. Unlike first-generation antihistamines, levocetirizine does not significantly cross the blood-brain barrier, resulting in minimal sedation at therapeutic doses.

Uses of (LARINEX 5MG TABLETS):

1. Symptomatic treatment of seasonal and perennial allergic rhinitis (sneezing, runny/itchy nose, itchy/watery eyes)
2. Management of chronic idiopathic urticaria (hives): reduces itching, redness, and wheal formation
3. Relief from other allergic skin conditions (e.g., pruritus)

Key Benefits of (LARINEX 5MG TABLETS):

1. Non-sedating in most individuals—safe for daytime use
2. Rapid onset of action (within 1 hour)
3. Long duration of effect—up to 24 hours
4. Once-daily dosing for improved adherence
5. Minimal anticholinergic side effects

How To Use (LARINEX 5MG TABLETS):

1. Take one tablet (5mg) once daily, preferably in the evening (though can be taken morning if no drowsiness occurs).
2. Swallow whole with water—can be taken with or without food.
3. For chronic urticaria or persistent allergies, use daily during exposure periods.
4. Do not exceed recommended dose.

When Not to Use (LARINEX 5MG TABLETS):

Do not use if you have:

1. Hypersensitivity to levocetirizine, cetirizine, or any excipients
2. Severe renal impairment (CrCl <10 mL/min)—contraindicated
3. End-stage renal disease on dialysis
4. History of urinary retention (use caution in elderly men with prostate enlargement)

Side Effects of (LARINEX 5MG TABLETS):

Common: Headache, dry mouth, fatigue, mild drowsiness (in sensitive individuals).

Rare: Abdominal pain, nausea, sore throat, weight gain.

Serious (very rare): Hypersensitivity reactions (angioedema, rash), palpitations.

Discontinue and seek medical help if facial swelling, difficulty breathing, or severe rash occurs.

Dosage: (LARINEX 5MG TABLETS):

1. Adults & children ≥12 years: 5mg once daily
2. Mild to moderate renal impairment (CrCl 30–50 mL/min): 2.5mg once daily
3. Severe renal impairment (CrCl <30 mL/min): Contraindicated
4. Not recommended for children under 6 years (use syrup formulation if needed)

Who It’s For (LARINEX 5MG TABLETS):

Adults and adolescents with seasonal allergies, year-round allergic rhinitis, or chronic hives who require non-drowsy, once-daily relief. Ideal for students, drivers, and professionals.

Warnings & Precautions:

1. May cause drowsiness in some individuals—avoid driving if affected
2. Use cautiously in elderly patients with reduced kidney function
3. Avoid alcohol—may enhance CNS depression
4. Not a treatment for anaphylaxis—epinephrine is required in emergencies

Drug Interactions:

1. Theophylline: May reduce clearance of levocetirizine
2. CNS depressants (alcohol, sedatives): Additive drowsiness (rare)
3. No significant CYP450 interactions
4. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date on the blister pack. Available over-the-counter in Pakistan.