Product Information:

INSUGET N Vials contain Neutral Protamine Hagedorn (NPH) Insulin, an intermediate-acting human insulin. NPH insulin is formulated with protamine and zinc to delay absorption, providing a basal (background) insulin effect that helps control blood glucose levels between meals and overnight.

It appears as a cloudy white suspension and must be gently resuspended before each use.

Uses of (INSUGET N VIALS):

1. Basal insulin coverage in type 1 and type 2 diabetes mellitus
2. Part of a basal-bolus regimen (combined with short- or rapid-acting insulin)
3. Twice-daily insulin regimens (e.g., with regular insulin)
4. Cost-effective alternative to long-acting insulin analogs (e.g., glargine, detemir)

Key Benefits of (INSUGET N VIALS):

1. Provides stable background insulin for 12–18 hours
2. Lower cost compared to insulin analogs
3. Flexible dosing (once or twice daily based on need)
4. Compatible with vial-and-syringe administration

How To Use (INSUGET N VIALS):

1. Gently roll the vial between palms until uniformly cloudy—do not shake vigorously (to avoid frothing).
2. Administer subcutaneously (abdomen, thigh, or upper arm).
3. Typical dosing: Once or twice daily (e.g., morning and/or bedtime).
4. Rotate injection sites to prevent lipodystrophy.
5. Do not administer intravenously unless in emergency settings under medical supervision.
6. Never share vials or syringes.

When Not to Use (INSUGET N VIALS):

Do not use if you have:

1. Hypersensitivity to human insulin or excipients (e.g., protamine, zinc, metacresol, glycerol)
2. Episodes of hypoglycemia without awareness
3. During diabetic ketoacidosis (use short-acting insulin IV instead)

Side Effects of (INSUGET N VIALS):

Common: Hypoglycemia (sweating, tremor, dizziness, hunger), injection site reactions (redness, itching, fat atrophy/hypertrophy).

Rare: Weight gain, peripheral edema, allergic skin reactions.

Serious (rare):

1. Severe hypoglycemia (confusion, seizures, unconsciousness)
2. Generalized hypersensitivity (anaphylaxis—angioedema, bronchospasm)
3. Hypokalemia (insulin shifts potassium into cells)
4. Seek emergency care for severe hypoglycemia or anaphylaxis.

Dosage: (INSUGET N VIALS):

1. Individualized based on weight, diet, activity, and glycemic targets.
2. Typical starting dose: 0.3–0.5 units/kg/day, divided once or twice daily.
3. Adjust based on fasting and pre-meal blood glucose levels.
4. Onset: 1–2 hours | Peak: 4–12 hours | Duration: 12–18 hours

Who It’s For (INSUGET N VIALS):

Adults and adolescents with type 1 or type 2 diabetes who require basal insulin coverage and are using vial-and-syringe delivery. Ideal for patients seeking a low-cost insulin option.

Warnings & Precautions:

1. Hypoglycemia risk increases with delayed meals, alcohol, or intense exercise
2. Monitor blood glucose regularly—especially during dose adjustments
3. Do not use if vial shows clumping, frosting, or discoloration
4. Cold insulin may cause pain—allow to reach room temperature before injection
5. Inform your doctor during illness, surgery, or changes in routine

Drug Interactions:

1. Beta-blockers: May mask tachycardia—a key sign of hypoglycemia
2. Corticosteroids, thiazides, sympathomimetics: May reduce insulin effectiveness
3. ACE inhibitors, salicylates, sulfonamides: May enhance hypoglycemic effect
4. Always inform your doctor about all medications.

Additional Information:

Store unopened vials in a refrigerator (2–8°C). Once in use, keep at room temperature (<30°C) for up to 28 days. Protect from light and heat. Do not freeze. Available by prescription in Pakistan.