Product Information:

FEXET 120mg Tablets contain Fexofenadine Hydrochloride 120mg, a second-generation antihistamine used for the relief of symptoms associated with allergic conditions. Fexofenadine is a selective peripheral H1-receptor antagonist that does not cross the blood-brain barrier significantly, making it non-sedating in most individuals. It is the active metabolite of terfenadine and is widely used due to its favorable safety profile.

Uses of (FEXET 120MG TABLETS):

1. Symptomatic treatment of seasonal allergic rhinitis (hay fever): sneezing, runny or itchy nose, itchy/watery eyes
2. Management of chronic idiopathic urticaria (hives): reduces itching, redness, and wheal formation
3. Relief from other allergic skin reactions (e.g., pruritus)

Key Benefits of (FEXET 120MG TABLETS):

1. Non-sedating—minimal drowsiness compared to first-generation antihistamines
2. Rapid onset of action (within 1–3 hours)
3. Long duration of effect—up to 24 hours
4. No significant cardiac toxicity (unlike its predecessor terfenadine)
5. Safe for daily use during allergy seasons

How To Use (FEXET 120MG TABLETS):

1. Take one tablet (120mg) once daily with water.
2. For allergic rhinitis: take as needed or daily during pollen season.
3. For chronic urticaria: may be prescribed once or twice daily (60mg twice daily in some cases).
4. Take on an empty stomach (at least 1 hour before or 2 hours after meals) for optimal absorption.
5. Avoid taking with fruit juices (e.g., apple, orange, grapefruit)—they can reduce drug absorption by up to 40%.

When Not to Use (FEXET 120MG TABLETS):

Do not use if you have:

1. Hypersensitivity to fexofenadine or any excipients
2. Severe renal impairment (CrCl <30 mL/min)—dose adjustment required
3. Phenylketonuria (PKU)—some formulations may contain aspartame (check excipients)

Side Effects of (FEXET 120MG TABLETS):

Common: Headache, dizziness, mild nausea, fatigue, dry mouth.

Rare: Insomnia, menstrual cramps, dyspepsia.

Serious (very rare): Hypersensitivity reactions (rash, angioedema), palpitations.

Fexofenadine is generally well-tolerated with no significant sedation or anticholinergic effects.

Dosage: (FEXET 120MG TABLETS):

1. Adults & adolescents (≥12 years): 120mg once daily for seasonal allergic rhinitis
2. Chronic urticaria: 180mg once daily or 60mg twice daily (as prescribed)
3. Renal impairment (CrCl <30 mL/min): Reduce to 60mg once daily
4. Not recommended for children under 12 years (use age-appropriate formulations)

Who It’s For (FEXET 120MG TABLETS):

Adults and adolescents with seasonal allergies or chronic hives who require non-drowsy, long-acting relief. Ideal for students, drivers, and professionals needing alertness.

Warnings & Precautions:

1. Avoid co-administration with aluminum/magnesium-containing antacids within 2 hours (reduces absorption)
2. Use caution in elderly patients with reduced kidney function
3. Not a treatment for anaphylaxis—epinephrine is required in such emergencies

Drug Interactions:

1. Antacids (Al/Mg hydroxide): ↓ Fexofenadine absorption—space doses by ≥2 hours
2. Fruit juices (apple, orange, grapefruit): ↓ Absorption—take with water only
3. Ketoconazole or erythromycin: May slightly increase fexofenadine levels (not clinically significant)
4. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date on the blister pack. Available over-the-counter in Pakistan.