Product Information:

DAPRODU 2mg Tablets contain Dapagliflozin 2mg, a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by inhibiting glucose reabsorption in the kidneys, leading to increased urinary glucose excretion and reduced blood glucose levels in adults with type 2 diabetes mellitus.

⚠️ Important Note:

The standard and globally approved dose of dapagliflozin is 10mg once daily. A 2mg strength is not recognized in major regulatory guidelines (FDA, EMA, WHO) and is not commercially available internationally. This formulation likely represents a local labeling variation or dispensing error in Pakistan. Dapagliflozin 2mg is considered subtherapeutic and may not provide adequate glycemic control.

Assuming this product contains dapagliflozin, the following information reflects standard pharmacology—with emphasis on verifying the correct dose.

Uses of (DAPRODU 2MG TAB):

1. Not clinically effective at 2mg for any approved indication
2. Standard dapagliflozin (10mg) is indicated for:
3. Type 2 diabetes mellitus (as monotherapy or add-on therapy)
4. Heart failure with reduced ejection fraction (HFrEF)—to reduce hospitalization and cardiovascular death
5. Chronic kidney disease (CKD) with albuminuria—to slow progression

❗ Recommendation: Confirm with your doctor or pharmacist whether this should be DAPRODU 10mg. A 2mg dose is unlikely to achieve therapeutic benefit.

Key Benefits of (Standard Dapagliflozin 10mg):

1. Lowers HbA1c by 0.5–1.0%
2. Promotes modest weight loss (2–3 kg) and reduces blood pressure
3. Proven cardio- and renoprotective effects—even in non-diabetics with HFrEF or CKD
4. Once-daily oral dosing

How To Use (If Confirmed as Dapagliflozin):

1. Take once daily in the morning, with or without food.
2. Swallow whole with water.
3. Therapeutic dose: 10mg once daily
4. 2mg dose: Likely insufficient—do not substitute without medical advice

When Not to Use (DAPRODU 2MG TAB):

Do not use if you have:

1. Type 1 diabetes or diabetic ketoacidosis
2. Severe renal impairment (eGFR <30 mL/min)
3. History of necrotizing fasciitis of the perineum (Fournier’s gangrene)
4. Hypersensitivity to dapagliflozin

Side Effects (More Relevant at 10mg; Reduced Risk at 2mg):

Common (at therapeutic doses):

1. Genital yeast infections (e.g., vulvovaginal candidiasis, balanitis)
2. Urinary tract infections
3. Increased urination (polyuria)

Serious (rare, but possible even at low doses):

1. Euglycemic diabetic ketoacidosis (nausea, vomiting, abdominal pain)—can occur with normal blood sugar
2. Fournier’s gangrene (severe genital/periurethral pain, swelling, fever)—medical emergency
3. Volume depletion (dizziness, hypotension)—especially in elderly or on diuretics

Dosage:

1. Approved dose: 10mg once daily
2. 2mg dose: Subtherapeutic—verify prescription accuracy

Who It’s For:

Adults with type 2 diabetes, HFrEF, or CKD—but only at 10mg dose.

Warnings & Precautions:

1. Monitor for signs of ketoacidosis, especially during illness, surgery, or fasting
2. Maintain adequate fluid intake
3. Assess renal function before and during treatment
4. Discontinue temporarily before major surgery

Drug Interactions:

1. Diuretics: May increase risk of dehydration and hypotension
2. Insulin or sulfonylureas: May slightly increase hypoglycemia risk
3. Always inform your doctor about all medications.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date. Available by prescription in Pakistan.