Product Information:

CYTOPAN 75mg Tablets contain Cyproheptadine Hydrochloride as the active ingredient, a first-generation antihistamine with potent antiserotonergic (5-HT2 antagonist) and anticholinergic properties. This higher-strength formulation is primarily used for appetite stimulation and weight gain in adults with significant undernutrition, cachexia due to chronic illness (e.g., cancer, tuberculosis), or post-illness recovery. It also provides relief from allergic conditions such as chronic urticaria and pruritus.

Uses of (CYTOPAN 75MG TABLETS):

1. Appetite enhancement and weight restoration in severely underweight or cachectic adults
2. Management of chronic idiopathic urticaria and allergic skin conditions
3. Adjunctive therapy in serotonin-related disorders (under specialist supervision)
4. Off-label use in migraine prophylaxis and cyclical vomiting syndrome

Key Benefits of (CYTOPAN 75MG TABLETS):

1. High-potency dose for significant appetite stimulation
2. Dual action: blocks histamine (H1) and serotonin (5-HT2) receptors
3. Promotes lean body mass gain in malnourished patients
4. Effective in refractory allergic itching unresponsive to newer antihistamines

How To Use (CYTOPAN 75MG TABLETS):

Take as directed by your physician—typically one tablet (75mg) once daily at bedtime due to its sedative effect. Swallow whole with water. Do not exceed the prescribed dose. Use for short-term periods (4–8 weeks); long-term use requires medical supervision and periodic reassessment.

When Not to Use (CYTOPAN 75MG TABLETS):

Do not use if you have:

1. Hypersensitivity to cyproheptadine or any excipients
2. Narrow-angle glaucoma
3. Urinary retention or severe prostatic hypertrophy
4. Peptic ulcer disease or pyloric stenosis
5. Pregnancy (especially third trimester) or breastfeeding
6. Concurrent use of monoamine oxidase inhibitors (MAOIs)

Side Effects of (CYTOPAN 75MG TABLETS):

Common: Drowsiness, dizziness, dry mouth, constipation, blurred vision, increased appetite, weight gain.

Serious (rare): Confusion, hallucinations, tachycardia, seizures, liver dysfunction, or acute angle-closure glaucoma. Discontinue and seek immediate medical help if eye pain, difficulty urinating, severe dizziness, or mental status changes occur.

Dosage: (CYTOPAN 75MG TABLETS):

1. Adults: 75mg once daily at night (maximum 150mg/day in divided doses, rarely used)
2. Duration: Typically 4–8 weeks; prolonged use only under strict medical supervision
3. Not for children—pediatric formulations (e.g., 4mg tablets/syrup) are available for younger patients

Who It’s For (CYTOPAN 75MG TABLETS):

Severely underweight adults, cancer or TB patients with cachexia, or individuals with chronic allergies requiring high-dose antihistamine/antiserotonergic therapy. Not intended for mild appetite loss or pediatric use.

Warnings & Precautions:

May cause significant drowsiness—avoid driving or operating heavy machinery. Use cautiously in elderly patients (increased risk of confusion, falls, urinary retention). Avoid alcohol (enhances CNS depression). Monitor weight, liver function, and metabolic parameters during extended therapy.

Drug Interactions:

1. CNS depressants (alcohol, benzodiazepines, opioids): Additive sedation and respiratory depression
2. Anticholinergics (e.g., atropine, tricyclic antidepressants): Increased risk of constipation, urinary retention, and heat intolerance
3. MAOIs: Potentiated anticholinergic effects—avoid concurrent use
4. Always inform your doctor about all medications and supplements.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the blister pack. Available by prescription in Pakistan.