Product Information:

COVA 80mg Tablets contain Valsartan as the active ingredient, an angiotensin II receptor blocker (ARB) that selectively inhibits the AT1 subtype of angiotensin II receptors. This leads to vasodilation, reduced aldosterone secretion, and decreased peripheral vascular resistance, effectively lowering blood pressure and reducing cardiac workload. The 80mg strength is commonly used as a starting dose or maintenance therapy for hypertension and heart-related conditions.

Uses of (COVA 80MG TABLETS):

1. Treatment of essential hypertension (high blood pressure)
2. Management of chronic heart failure (as part of combination therapy)
3. Reduction of cardiovascular risk in stable patients following myocardial infarction (heart attack) with left ventricular dysfunction
4. Renal protection in patients with type 2 diabetes and proteinuria (off-label, under specialist supervision)

Key Benefits of (COVA 80MG TABLETS):

1. Once-daily dosing for consistent 24-hour blood pressure control
2. Does not cause dry cough (a common side effect of ACE inhibitors)
3. Cardioprotective and renoprotective effects beyond blood pressure reduction
4. Well-tolerated with minimal side effects
5. Improves survival outcomes in heart failure and post-MI patients

How To Use (COVA 80MG TABLETS):

Take one tablet once daily at the same time each day, with or without food. Swallow whole with water—do not crush or chew. Continue taking regularly, even if you feel well, as high blood pressure often has no symptoms. Do not discontinue without medical advice.

When Not to Use (COVA 80MG TABLETS):

Do not use if you have:

1. Known hypersensitivity to valsartan or any excipients
2. Pregnancy (especially second and third trimesters—risk of fetal injury or death)
3. Severe liver impairment or biliary obstruction
4. Concomitant use of aliskiren in diabetic patients
5. Bilateral renal artery stenosis or solitary kidney with renal artery stenosis

Side Effects of (COVA 80MG TABLETS):

Common: Dizziness, headache, fatigue, low blood pressure (especially during initial treatment), or mild elevation in potassium levels.

Serious (rare): Angioedema (swelling of face, lips, tongue, or throat), acute kidney injury, symptomatic hypotension, or hyperkalemia. Seek emergency care if breathing difficulty, severe dizziness, or facial swelling occurs.

Dosage: (COVA 80MG TABLETS):

1. Hypertension: Starting dose is often 80mg once daily; may be increased to 160–320mg based on response
2. Heart failure: Typically initiated at 40mg twice daily, titrated up as tolerated
3. Post-MI: Started at 20mg twice daily, gradually increased to target dose
4. Always follow your physician’s prescribed regimen.

Who It’s For (COVA 80MG TABLETS):

Adults with newly diagnosed or mild hypertension, heart failure, or post-heart attack care. Ideal for patients switching from ACE inhibitors due to cough. Not for children under 6 years or pregnant women.

Warnings & Precautions:

Monitor kidney function and serum potassium periodically, especially in elderly patients or those with heart/kidney disease. Avoid potassium supplements or salt substitutes containing potassium unless directed. Dehydration (from diuretics, vomiting, or diarrhea) may cause excessive blood pressure drop—maintain adequate fluid intake.

Drug Interactions:

1. Potassium-sparing diuretics (e.g., spironolactone): ↑ Risk of hyperkalemia
2. NSAIDs (e.g., ibuprofen, celecoxib): May reduce antihypertensive effect and impair kidney function
3. Lithium: Valsartan may increase lithium levels—monitor closely
4. ACE inhibitors + Aliskiren: Triple blockade increases risk of renal failure and hyperkalemia
5. Always inform your doctor about all medications and supplements.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the blister pack. Available by prescription in Pakistan.