Product Information:

CLARITEK 250mg/5mL Granules for Oral Suspension (70mL) contain Clarithromycin as the active ingredient, a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. This pediatric formulation is supplied as flavored granules to be reconstituted into a suspension, offering accurate dosing for infants and children who cannot swallow tablets. It is effective against a broad range of Gram-positive, Gram-negative, and atypical bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma, and Helicobacter pylori.

Uses of (CLARITEK 250MG/5ML GRANULE 70ML):

1. Pharyngitis, tonsillitis, and sinusitis in children
2. Acute otitis media (middle ear infection)
3. Community-acquired pneumonia and bronchitis
4. Skin and soft tissue infections
5. Helicobacter pylori eradication in combination therapy (in older children under specialist care)

Key Benefits of (CLARITEK 250MG/5ML GRANULE 70ML):

1. Precise weight-based dosing for infants and young children
2. Palatable, flavored suspension for better acceptance
3. Broad-spectrum activity including atypical pathogens
4. Acid-stable—well absorbed with or without food
5. Convenient 70mL bottle for full-course treatment

How To Use (CLARITEK 250MG/5ML GRANULE 70ML):

1. Reconstitution: Add purified water up to the marked line (usually ~55–60mL), shake well until uniform.
2. Dosage: Based on body weight—typically 7.5 mg/kg every 12 hours (max 500mg/dose).
3. Concentration: 250mg per 5mL = 50mg/mL
4. Example: A 15 kg child receives 112.5 mg/dose → 2.25 mL twice daily
5. Shake well before each use. Administer with or without food. Complete the full course (7–14 days).

When Not to Use (CLARITEK 250MG/5ML GRANULE 70ML):

Do not use if the child has:

1. Hypersensitivity to clarithromycin, erythromycin, or other macrolides
2. History of QT prolongation or cardiac arrhythmias
3. Concomitant use of cisapride, pimozide, or ergotamine derivatives
4. Severe liver disease with renal impairment

Side Effects of (CLARITEK 250MG/5ML GRANULE 70ML):

Common: Diarrhea, nausea, abdominal pain, vomiting, altered taste, diaper rash.

Serious (rare): Prolonged QT interval, hepatotoxicity, severe skin reactions (e.g., Stevens-Johnson syndrome), or Clostridioides difficile-associated colitis. Discontinue and seek medical help if persistent watery stools, jaundice, rash, or irregular heartbeat occur.

Dosage: (CLARITEK 250MG/5ML GRANULE 70ML):

1. Standard pediatric dose: 7.5 mg/kg every 12 hours
2. Maximum: 500mg per dose
3. Duration: 7–14 days depending on infection
4. Use only the provided measuring syringe or spoon. Do not exceed prescribed dose.

Who It’s For (CLARITEK 250MG/5ML GRANULE 70ML):

Infants (≥6 months) and children up to 12 years with bacterial respiratory, ear, or skin infections requiring macrolide therapy—especially when penicillin allergy is present. Not for neonates under 6 months unless directed by a pediatrician.

Warnings & Precautions:

Use cautiously in children with liver disease or history of prolonged QT syndrome. Monitor for signs of superinfection or allergic reaction. Avoid in myasthenia gravis (may worsen symptoms). Ensure full reconstitution and proper storage after mixing.

Drug Interactions:

1. CYP3A4 substrates (e.g., theophylline): Increased levels
2. Anticoagulants: May enhance effect
3. Colchicine (in renal impairment): Risk of toxicity
4. Always inform your pediatrician about all medications or supplements.

Additional Information:

Store dry granules below 25°C. After reconstitution, refrigerate (2–8°C) and use within 14 days. Shake well before each dose. Keep out of reach of children. Available by prescription in Pakistan.