Product Information:

CIPESTA 250mg/5mL Suspension is a high-strength pediatric and adult antibiotic formulation containing Ciprofloxacin, a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV—essential enzymes for DNA replication and repair. This results in rapid bactericidal activity against a broad spectrum of Gram-negative bacteria, including Pseudomonas aeruginosa, E. coli, Klebsiella, and Salmonella species. The suspension is flavored for better palatability and is intended for patients who cannot swallow solid dosage forms.

Uses of (CIPESTA 250MG /5ML SUSPENSION):

1. Complicated urinary tract infections (UTIs) and pyelonephritis
2. Severe bacterial gastroenteritis (e.g., due to Salmonella, Shigella)
3. Respiratory tract infections caused by susceptible Gram-negative organisms
4. Post-exposure prophylaxis for inhalational anthrax
5. Other serious infections when oral therapy is needed and no safer alternative exists

Key Benefits of (CIPESTA 250MG /5ML SUSPENSION):

1. High concentration (250mg/5mL = 50mg/mL) reduces dosing volume
2. Broad-spectrum coverage against resistant Gram-negative pathogens
3. Suitable for older children, adolescents, and adults unable to take tablets
4. Ready-to-use liquid format with calibrated dosing device
5. Effective tissue penetration into urine, gut, and respiratory tract

How To Use (CIPESTA 250MG /5ML SUSPENSION):

Shake well before each use. Administer orally with or without food—but avoid dairy products, calcium-fortified juices, antacids, iron, or zinc supplements within 2 hours (they significantly reduce absorption).

1. Adults & adolescents (≥12 years): 250–500mg every 12 hours → 5–10 mL twice daily
2. Children (1–17 years): 10–20 mg/kg/day in two divided doses (max 750mg/day)
3. Complete the full course (typically 7–14 days), even if symptoms improve early.

When Not to Use (CIPESTA 250MG /5ML SUSPENSION):

Do not use if:

1. Hypersensitive to ciprofloxacin or other fluoroquinolones
2. History of tendon disorders or myasthenia gravis
3. Pregnant, breastfeeding, or in children under 1 year
4. Concomitant use of tizanidine (contraindicated)
5. Fluoroquinolones are reserved for serious infections only due to risk of tendon/cartilage damage and neuropathy.

Side Effects of (CIPESTA 250MG /5ML SUSPENSION):

Common: Nausea, diarrhea, abdominal discomfort, mild rash.

Serious (rare): Tendon pain/rupture, joint swelling (arthropathy), peripheral neuropathy, dizziness, photosensitivity, or Clostridioides difficile colitis. Discontinue and seek medical help if joint/tendon pain, numbness, or severe diarrhea occurs.

Dosage: (CIPESTA 250MG /5ML SUSPENSION):

1. Concentration: 250mg per 5mL = 50mg/mL
2. Adult dose: 250–500mg every 12 hours → 5–10 mL twice daily
3. Pediatric dose: 10–20 mg/kg/day in 2 divided doses
4. Use only the provided measuring device. Do not exceed prescribed duration.

Who It’s For (CIPESTA 250MG /5ML SUSPENSION):

Adolescents (≥12 years) and adults requiring high-dose oral ciprofloxacin but unable to swallow tablets. May be used in younger children (1–11 years) only under strict pediatric supervision for life-threatening Gram-negative infections with no alternatives.

Warnings & Precautions:

Fluoroquinolones carry black-box warnings for irreversible tendon damage, neuropathy, and CNS effects. Avoid sun exposure (photosensitivity). Not for uncomplicated UTIs, sinusitis, or bronchitis. Monitor for joint pain, especially in growing children.

Drug Interactions:

1. Dairy, antacids, iron, zinc: Reduce absorption—give ≥2 hours apart
2. Theophylline: Risk of seizures
3. Warfarin: Increased bleeding risk
4. NSAIDs: May trigger CNS stimulation or seizures
5. Always disclose all medications to your doctor.

Additional Information:

Store below 25°C. After reconstitution (if powder), refrigerate (2–8°C) and use within 14 days. Shake well before each dose. Keep out of reach of children. Available by prescription only in Pakistan.