Product Information:

CIPESTA 125mg/5mL Suspension is a pediatric antibiotic formulation containing Ciprofloxacin as the active ingredient, a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV—enzymes essential for DNA replication and repair. This suspension provides broad-spectrum activity against Gram-negative bacteria, including Pseudomonas aeruginosa, E. coli, and Salmonella species. It is specifically formulated for children who cannot swallow tablets and require oral antibiotic therapy for susceptible infections.

Uses of (CIPESTA 125MG/5ML SUSPENSION):

1. Complicated urinary tract infections (UTIs) in children
2. Pyelonephritis (kidney infection)
3. Gastroenteritis caused by susceptible Gram-negative organisms (e.g., Salmonella, Shigella)
4. Inhalational anthrax (post-exposure prophylaxis)
5. Other serious bacterial infections when no safer alternative is available

Key Benefits of (CIPESTA 125MG/5ML SUSPENSION):

1. Liquid formulation for accurate pediatric dosing
2. Effective against resistant Gram-negative pathogens
3. Rapid bactericidal action with good tissue penetration
4. Flavored for better acceptance in children
5. Reserved for infections where benefits outweigh risks

How To Use (CIPESTA 125MG/5ML SUSPENSION):

Shake well before each use. Administer orally with or without food—but avoid giving with dairy products, calcium-fortified juices, antacids, or iron supplements within 2 hours (they reduce absorption).

1. Pediatric dose: 10–20 mg/kg/day in two divided doses (max 750mg/day)
2. Concentration: 125mg per 5mL = 25mg/mL
3. Example: A 20 kg child receives 200–400mg/day → 8–16 mL/day total → 4–8 mL twice daily
4. Complete the full course even if symptoms improve early.

When Not to Use (CIPESTA 125MG/5ML SUSPENSION):

Do not use in children under 1 year or for mild/uncomplicated infections. Avoid if:

1. Hypersensitive to ciprofloxacin or other fluoroquinolones
2. History of tendon disorders or myasthenia gravis
3. Concomitant use of tizanidine
4. Fluoroquinolones are reserved for pediatric use only when no alternative exists due to risk of cartilage/joint damage in growing tissues.

Side Effects of (CIPESTA 125MG/5ML SUSPENSION):

Common: Nausea, diarrhea, abdominal pain, mild rash.

Serious (rare): Arthropathy (joint pain/swelling), tendonitis, peripheral neuropathy, CNS effects (dizziness, insomnia), photosensitivity, or Clostridioides difficile colitis. Discontinue and seek medical help if joint pain, severe diarrhea, or rash occurs.

Dosage: (CIPESTA 125MG/5ML SUSPENSION):

1. Usual pediatric dose: 10–20 mg/kg/day in 2 divided doses
2. Maximum: 750mg/day
3. Duration: 7–14 days based on infection
4. Always confirm dose with a pediatrician. Use only the provided measuring device.

Who It’s For (CIPESTA 125MG/5ML SUSPENSION):

Children aged 1–17 years with serious, culture-proven Gram-negative infections where safer antibiotics (e.g., cephalosporins) are ineffective or contraindicated. Not for routine ear/throat infections or viral illnesses.

Warnings & Precautions:

Fluoroquinolones may cause irreversible joint/cartilage damage in juvenile animals—use in children only under strict specialist supervision. Avoid sun exposure (photosensitivity). Monitor for signs of tendon/joint pain. Do not use for uncomplicated UTIs or traveler’s diarrhea in children.

Drug Interactions:

1. Antacids, iron, zinc, dairy: Reduce absorption—administer ≥2 hours apart
2. Theophylline: Increased levels → risk of seizures
3. NSAIDs: May increase CNS stimulation
4. Always inform your doctor about all medications/supplements.

Additional Information:

Store below 25°C. After reconstitution (if powder), refrigerate (2–8°C) and use within 14 days. Shake well before each dose. Keep out of reach of children. Available by prescription only in Pakistan.