Product Information:

CEFIGET 400mg Capsules contain Cefixime as the active ingredient, a third-generation oral cephalosporin antibiotic that inhibits bacterial cell wall synthesis. It offers enhanced activity against a broad spectrum of Gram-positive and Gram-negative bacteria, including beta-lactamase-producing strains. This high-strength formulation is ideal for moderate to severe infections or as a single-dose treatment for uncomplicated gonorrhea, providing convenient once-daily therapy with strong clinical efficacy.

Uses of (CEFIGET 400MG CAPSULES):

1. Treatment of pharyngitis, tonsillitis, and streptococcal throat infections
2. Management of acute bronchitis, sinusitis, and mild community-acquired pneumonia
3. Uncomplicated urinary tract infections (UTIs) caused by susceptible E. coli, Proteus, or Klebsiella
4. Acute otitis media in adults and older adolescents
5. Single-dose treatment of uncomplicated urogenital gonorrhea (as an alternative to injectable ceftriaxone)

Key Benefits of (CEFIGET 400MG CAPSULES):

1. High-potency dose for effective coverage in moderate infections
2. Once-daily dosing ensures better patient compliance
3. Resistant to common beta-lactamase enzymes
4. Excellent tissue penetration, including respiratory and genitourinary tracts
5. Suitable for patients with non-anaphylactic penicillin allergy

How To Use (CEFIGET 400MG CAPSULES):

Take one capsule once daily, with or without food. Swallow whole with water—do not crush or chew. For most infections, continue for 5–10 days. For gonorrhea, a single 400mg dose is typically sufficient under medical supervision. Complete the full course even if symptoms improve early to prevent relapse and antimicrobial resistance.

When Not to Use (CEFIGET 400MG CAPSULES):

Do not use if you have known hypersensitivity to cefixime, other cephalosporins, or penicillins (especially anaphylaxis). Avoid in severe renal impairment (CrCl <30 mL/min) without dose adjustment. Not indicated for viral infections like colds or flu.

Side Effects of (CEFIGET 400MG CAPSULES):

Common: Diarrhea, nausea, abdominal discomfort, headache, or mild rash.

Serious (rare): Severe allergic reactions (anaphylaxis), Clostridioides difficile-associated colitis (persistent watery/bloody stools), serum sickness-like reaction, or transient liver enzyme elevation. Discontinue and seek emergency care if breathing difficulty, severe skin reaction, or prolonged diarrhea occurs.

Dosage: (CEFIGET 400MG CAPSULES):

Standard adult dose: 400mg once daily.

In renal impairment (CrCl <60 mL/min): Reduce to 200mg every 48 hours.

For gonorrhea: Single 400mg dose (confirm local resistance patterns). Always follow your physician’s prescription.

Who It’s For (CEFIGET 400MG CAPSULES):

Adults and adolescents (≥12 years, ≥40 kg) with moderate bacterial infections requiring high-dose cephalosporin therapy. Not intended for young children, neonates, or severe systemic infections needing IV antibiotics.

Warnings & Precautions:

Use cautiously in patients with kidney disease or history of antibiotic-associated colitis. Prolonged use may lead to fungal superinfection (e.g., oral/vaginal thrush). Inform all healthcare providers about beta-lactam allergy history. If diarrhea persists beyond 2 days, consult a doctor.

Drug Interactions:

May reduce effectiveness of oral contraceptives—use backup contraception. Probenecid can increase cefixime levels. Concurrent use with nephrotoxic drugs (e.g., aminoglycosides) may elevate kidney risk. Always disclose all medications to your healthcare provider.

Additional Information:

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the blister pack. Available by prescription in Pakistan.