Product Information:

BASAGINE Injection Pen 100 Units/mL (3mL) is a ready-to-use, pre-filled auto-injector containing Glucagon, a hormone that rapidly increases blood glucose levels by stimulating glycogenolysis in the liver. Unlike traditional vial-and-syringe glucagon kits, this pen delivers a fixed dose instantly without reconstitution—making it ideal for emergency treatment of severe hypoglycemia in diabetic patients who are unconscious, seizing, or unable to take oral carbohydrates. The 3mL pen contains a total of 300 units (1 mg) of glucagon (since 1 mg = 100 units), designed for single-dose administration.

Uses of (BASAGINE INJ PEN 100 UNITS/ML 3ML):

1. Emergency treatment of severe hypoglycemia in insulin-treated patients with diabetes (Type 1 or Type 2).
2. Suitable for use by caregivers, family members, school staff, or first responders in out-of-hospital settings.
3. Alternative to traditional glucagon kits where speed and simplicity are critical.

Key Benefits of (BASAGINE INJ PEN 100 UNITS/ML 3ML):

1. No mixing or preparation required—ready to inject in seconds
2. Pre-measured dose eliminates dosing errors
3. Compact, portable design for home, school, or travel use
4. Works within 10–15 minutes to restore consciousness
5. Reduces anxiety and delays in emergency response

How To Use (BASAGINE INJ PEN 100 UNITS/ML 3ML):

1. Remove cap from the pen.
2. Press the injector firmly against the outer thigh (through clothing if necessary).
3. Hold in place for 5–10 seconds to ensure full dose delivery.
4. Turn the patient on their side and call emergency services immediately.
5. Once the patient regains consciousness, give fast-acting sugar (e.g., juice, glucose gel).
6. Do not reuse the pen. Dispose of properly after single use.

When Not to Use (BASAGINE INJ PEN 100 UNITS/ML 3ML):

Do not use in patients with known hypersensitivity to glucagon or lactose (excipient). Avoid in cases of hypoglycemia due to prolonged fasting, adrenal insufficiency, or chronic liver disease—where hepatic glycogen stores are depleted and glucagon will be ineffective. Not intended for conscious patients who can swallow oral glucose.

Side Effects of (BASAGINE INJ PEN 100 UNITS/ML 3ML):

Common: Nausea, vomiting, transient rapid heartbeat, headache, or dizziness.

Rare but serious: Allergic reactions (rash, swelling, difficulty breathing), especially in patients with pheochromocytoma or insulinoma. Hyperglycemia may occur post-recovery but typically resolves with hydration and monitoring.

Dosage: (BASAGINE INJ PEN 100 UNITS/ML 3ML):

1. Adults & children ≥25 kg: Full 3mL (300 units / 1 mg) as a single dose.
2. Children <25 kg: Half-pen dose (1.5 mL / 150 units / 0.5 mg) if device allows; otherwise, use pediatric formulation.
3. A second dose may be given after 15 minutes if no response and emergency help is delayed. Always follow with oral carbohydrates once alert.

Who It’s For (BASAGINE INJ PEN 100 UNITS/ML 3ML):

Diabetic patients at high risk of severe hypoglycemia—especially those on intensive insulin therapy, with hypoglycemia unawareness, or living alone. Also recommended for schools, workplaces, and caregivers. Not for neonates or non-diabetic hypoglycemia.

Warnings & Precautions:

Train all potential users in advance. Store at room temperature (do not freeze). Check expiry date regularly. Replace if solution appears cloudy or discolored. After use, seek immediate medical evaluation—even if the patient recovers fully. Patients should wear medical ID indicating diabetes and glucagon availability.

Drug Interactions:

Beta-blockers may mask tachycardia, delaying recognition of response. Indomethacin may reduce glucagon’s glucose-raising effect. Warfarin interaction may cause INR fluctuations. Inform healthcare providers of all medications.

Additional Information:

Store below 25°C, protected from light. Do not refrigerate or freeze. Keep in easily accessible location (e.g., bedside, handbag, school nurse kit). Single-use only. Available by prescription in Pakistan