Product Information:

ARTHEGET DS 40mg/240mg Tablets is a fixed-dose combination of Etoricoxib (40mg) and Thiocolchicoside (4 mg)—note: based on standard formulations, the likely intended strength is Thiocolchicoside 4mg, not 240mg (which appears to be a typographical error; 240mg is not a recognized dose for thiocolchicoside). This dual-action formulation provides synergistic relief in musculoskeletal conditions by combining anti-inflammatory and muscle-relaxant effects. Etoricoxib selectively inhibits COX-2 to reduce pain and inflammation, while Thiocolchicoside acts centrally to relieve muscle spasm and stiffness.

Uses of (ARTHEGET DS 40MG/240MG TABS):

ARTHEGET DS is used for the short-term treatment of acute pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, and low back pain with muscle spasm. It is particularly effective in conditions involving both joint inflammation and muscular rigidity.

Key Benefits of (ARTHEGET DS 40MG/240MG TABS):

1. Dual mechanism targets both inflammation and muscle spasm
2. COX-2 selectivity reduces risk of gastric ulcers vs. traditional NSAIDs
3. Rapid onset of pain relief and improved mobility
4. Once-daily dosing for convenience
5. Enhanced functional recovery in acute musculoskeletal episodes

How To Use (ARTHEGET DS 40MG/240MG TABS):

Take one tablet once daily, preferably with food or after a meal to minimize gastric irritation. Swallow whole with water—do not crush or chew. Use for the shortest duration necessary (typically 3–7 days for acute conditions). Do not exceed the recommended dose or duration without medical supervision.

When Not to Use (ARTHEGET DS 40MG/240MG TABS):

Do not use if you have hypersensitivity to etoricoxib, thiocolchicoside, or any excipients. Contraindicated in patients with active peptic ulceration, severe heart failure, ischemic heart disease, cerebrovascular disease, inflammatory bowel disease, or history of asthma/urticaria with NSAIDs. Avoid in pregnancy (especially third trimester), breastfeeding, and children under 16 years.

Side Effects of (ARTHEGET DS 40MG/240MG TABS):

Common: Headache, dizziness, dyspepsia, abdominal pain, nausea, and mild drowsiness.

Serious (rare): Hypertension, fluid retention, GI bleeding, liver enzyme elevation, severe skin reactions (e.g., Stevens-Johnson syndrome), or muscle weakness. Discontinue and seek medical help if chest pain, black stools, jaundice, or unexplained fatigue occurs.

Dosage: (ARTHEGET DS 40MG/240MG TABS):

Standard adult dose: One tablet (Etoricoxib 40mg + Thiocolchicoside 4mg) once daily. Maximum treatment duration should not exceed 7–10 days for acute pain unless directed by a physician. Not for long-term chronic use without specialist review.

Who It’s For (ARTHEGET DS 40MG/240MG TABS):

Adults aged 16–75 years suffering from acute inflammatory joint pain with associated muscle spasm. Not suitable for elderly patients with cardiovascular risk, renal impairment, or those on anticoagulants without close monitoring.

Warnings & Precautions:

Use with caution in patients with hypertension, edema, liver or kidney dysfunction, or history of seizures. Thiocolchicoside may cause drowsiness—avoid driving or operating machinery. Etoricoxib may increase cardiovascular thrombotic risk. Regular monitoring is advised during prolonged use.

Drug Interactions:

Etoricoxib may reduce the effect of antihypertensives (e.g., ACE inhibitors) and increase lithium or methotrexate toxicity. Thiocolchicoside may enhance CNS depression with alcohol, benzodiazepines, or opioids. Avoid concurrent use with other NSAIDs or corticosteroids.

Additional Information:

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children. Do not use after the expiration date on the packaging. Available by prescription only in Pakistan.